Publication list

Electrocardiographic Changes at the Early Stage of Status Epilepticus:
First Insights From the ICTAL Registry.

To describe early electrocardiogram (ECG) abnormalities after status epilepticus (SE) and evaluate their association with 90-day neurological outcomes.

Multicentre observational statusepilepticus registry:
protocol for ICTAL

Status epilepticus (SE) is a common lifethreatening neurological emergency that can cause longterm impairments. Overall outcomes remain poor. Major efforts are required to clarify the epidemiology of SE andthe determinants of outcomes, thereby identifying targets for improved management.

Nurses: The Missing Link in Continuous Electroencephalogram Monitoring?

The past decade has been marked by the advent of continuous EEG (cEEG) monitoring, which is now recommended as the standard of care in numerous medical conditions seen in the neurologic intensive care unit (ICU).

Considering postanoxic status epilepticus as a potential modifiable factor and treatment target: A step forward

The main factor determinant of outcomes following cardiac arrest is the degree of
global brain injury resulting from circulation standstill (primary insult) and the ongoing injury related to mismatches between cerebral energy supply and demand despite resumption of forward blood flow (secondary brain injury).

Tiagabine-related status epilepticus:
a case report and systematic literature review

Tiagabine-related status epilepticus (SE) is an uncommon complication of tiagabine use.
We aimed to detail the features and outcomes in a patient with tiagabine poisoning and review the relevant literature. 

The Role of Secondary Brain Insults in Status Epilepticus: A Systematic Review

Status epilepticus (SE) is a major medical condition that is associated with poor outcome in approximately 50% of cases, despite the use of conventional anticonvulsive treatments. The age of the patients, a previous history of epilepsy, SE refractoriness, and a primary cerebral insult as the cause of
SE have been identified as independent predictors of poor outcome

Epileptic Seizures in Critically Ill Patients: Diagnosis,
Management, and Outcomes

Seizures may be convulsive or nonconvulsive. They may also be prolonged in duration reaching the diagnosis criteria for status
epilepticus. They can occur in various settings, and can involve a large spectrum of multidisciplinary teams, including but not limited to medical physicians and nurses
from emergency departments,
operating rooms, or intensive and neurocritical care units.

Teaching Important Basic EEG Patterns of Bedside Electroencephalography to Critical Care Staffs: A Prospective Multicenter Study

Continuous electroencephalography (cEEG)
is commonly recommended for neurocritical care patients. Routine implementation of such monitoring requires the specific training of professionals. The aim of this research was to evaluate the effectiveness of a training program on initiation of the basic interpretation of cEEG for critical care staff in a prospective multicenter study. 

Hypothermia as an adjuvant treatment in paediatric refractory or super-refractory status epilepticus

Therapeutic hypothermia is among the adjuvant therapies suggested for refractory or super-refractory status epilepticus (R/SR-SE) in paediatric patients. Experimental evidence of neuroprotective and antiseizure effects provides a strong rationale for using therapeutic hypothermia in patients with status epilepticus.

Second-line anticonvulsant for convulsive status epilepticus: The dosage matters!

Hypothermia as a treatment in status epilepticus: A narrative review

Status epilepticus (SE) is associated with high mortality and morbidity rates, notably in its refractory and super-refractory forms. This narrative review discusses recent data on the potential benefits of targeted temperature management. In studies of patients with cerebral injury due to various factors, therapeutic hypothermia had variable effects on survival and functional outcomes.

Comparison of etomidate and sodium thiopental for induction during rapid sequence intubation in convulsive status epilepticus: A retrospective single-center study

ew outcome data are available about morbidity associated with endotracheal intubation modalities in critically ill patients with convulsive status epilepticus. We compared etomidate versus sodium thiopental for emergency rapid sequence intubation in patients with out-of-hospital convulsive status epilepticus.